Dynamics of integral hematological indices of fish in chronic intoxication

Today, laboratory practice has a rich arsenal of methods for dynamic control over the course of pathological processes in the body of fish. Quantitative indicators of blood leukocytes and, especially, indicators of its leukocyte formula are important re-search methods in the diagnosis of a wide variety of pathological conditions. To objectively assess these results, a number of indicators have now been proposed that determine the course of pathological processes in the body, but these indicators are not used in real fisheries science and aquaculture.The purpose of our study was to study the dynamics of integral hematological indices of fish against the background of chronic experimental intoxication.As a result of the research, it was found that the use of hematological indices in fish can provide additional information about the course of the toxic process, including the course of pathological processes of other etiology. It was revealed that the deter-mination of integral leukocyte indices can be an addition or alternative to complex immunological and biochemical studies.