Development and validation of a prediction model based on two-dimensional dose distribution maps fused with computed tomography images for noninvasive prediction of radiochemotherapy resistance in non-small cell lung cancer

Compared to the traditional radiomics model, the 2D dosiomics model demonstrates superior predictive performance. The combined model based on clinical data, radiomics, and dosiomics has improved the prediction of radiochemotherapy resistance in NSCLC and effectively performed survival stratification. Through precise risk assessment, doctors can better understand which patients may develop resistance to treatment and optimize treatment plans accordingly.

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Publication Details

Journal
Translational Cancer Research
Published
2025-03-01
DOI
https://doi.org/10.21037/tcr-24-1897
Primary Topic
Medical Imaging Techniques and Applications
Type
article
Field-Weighted Citation Impact
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article

Development and validation of a prediction model based on two-dimensional dose distribution maps fused with computed tomography images for noninvasive prediction of radiochemotherapy resistance in non-small cell lung cancer

Tony He, Benlan Li, Xia Ji, Bing Lü et al.
Translational Cancer Research
Medical Imaging Techniques and Applications
article

Development and validation of a prediction model based on two-dimensional dose distribution maps fused with computed tomography images for noninvasive prediction of radiochemotherapy resistance in non-small cell lung cancer

Tony He, Benlan Li, Xia Ji, Bing Lü, Y. J. Mo, Bo Du, Fangyang Lu, Yongxiang Hu, Zhongjun Huang, Ya Li, Yang Yang, Jie Peng, Min Zhang
article en

Abstract

Compared to the traditional radiomics model, the 2D dosiomics model demonstrates superior predictive performance. The combined model based on clinical data, radiomics, and dosiomics has improved the prediction of radiochemotherapy resistance in NSCLC and effectively performed survival stratification. Through precise risk assessment, doctors can better understand which patients may develop resistance to treatment and optimize treatment plans accordingly.

Translational Cancer ResearchVol. 14(3)
Guiyang Medical University (CN), Shanghai Public Health Clinical Center (CN), Affiliated Hospital of Guizhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 92%
Medical Imaging Techniques and Applications
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Development and validation of a prediction model based on two-dimensional dose distribution maps fused with computed tomography images for noninvasive prediction of radiochemotherapy resistance in non-small cell lung cancer — Tony He, Benlan Li, et al. · Translational Cancer Research (2025) | TGRS Research Map | TGRS