Akkermansia muciniphila Delays the Progression of Diabetic Nephropathy by Reducing the Accumulation of Uremic Toxins in the Feces and Peripheral Blood
Exogenous supplementation of A. muciniphila improved the imbalance of gut microbiota, reduced systemic inflammation, decreased uremic toxins, and protected the integrity of the intestinal mucosa, thus delaying DKD progression.
Authors
- Xixi Song (ORCID: https://orcid.org/0000-0001-7168-8146)
- Bo Huang (ORCID: https://orcid.org/0000-0002-3088-9328)
- Jingqiu Cui (ORCID: https://orcid.org/0000-0002-7568-3622)
- Jing Zhang (ORCID: https://orcid.org/0000-0001-9617-9305)
- Xin Li (ORCID: https://orcid.org/0000-0002-7414-5734)
- Mingyan Yao (ORCID: https://orcid.org/0000-0002-0392-2495)
- Mengjuan Zhang (ORCID: https://orcid.org/0000-0002-5095-414X)
Institutions
- Tianjin Medical University General Hospital (CN)
- Affiliated Hospital of Hebei University (CN)
- Baoding People's Hospital (CN)
- Baoding No.1 Central Hospital
Publication Details
- Journal
- Endocrine Metabolic & Immune Disorders - Drug Targets
- Published
- 2025-03-20
- DOI
- https://doi.org/10.2174/0118715303343599250210103212
- Citations
- 2
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.61