Deficiency of Toll-like receptor 4 attenuates airway inflammation and remodeling in an ovalbumine-induced mouse asthma model
These results demonstrate that TLR4 deficiency attenuates airway inflammation and remodeling, potentially through the inhibition of the TLR4/NF-κB signaling pathway in an OVA-induced mouse asthma model.
Authors
- Bingxi Zhang
- Zhimei Li (ORCID: https://orcid.org/0000-0003-3185-8790)
- Yao Dong (ORCID: https://orcid.org/0000-0001-8883-5384)
- Bo Xiao (ORCID: https://orcid.org/0000-0002-2992-6435)
- Biwen Mo (ORCID: https://orcid.org/0000-0003-3667-0076)
- Lixia Hou (ORCID: https://orcid.org/0000-0002-2090-2859)
- Sijia Song
- Xinru Feng
Institutions
- Guilin Medical University (CN)
- Xianning Central Hospital (CN)
- Hubei University of Science and Technology (CN)
Publication Details
- Journal
- Journal of Thoracic Disease
- Published
- 2025-03-01
- DOI
- https://doi.org/10.21037/jtd-24-1751
- Citations
- 3
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 2.39