Mid-infrared photoacoustic spectroscopy detecting continuous ultrasound for non-invasive tissue component analysis (Conference Presentation)

Photoacoustic spectroscopy using mid-infrared light enables non-invasive analysis of biological tissue components. In photoacoustic spectroscopy, which detects ultrasonic waves generated by irradiation with pulsed infrared light, a method of inducing resonance by varying the pulse modulation frequency was investigated. This method was used to obtain photoacoustic spectra of human skin. Pre- and post-prandial measurements were performed over several days to investigate the feasibility of analysing blood components. The results showed that changes in measurement site, shape and daily baseline made the analysis of blood components difficult. Therefore, an investigation to reduce spectral variability is also being carried out.

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Publication Details

Published
2025-03-20
DOI
https://doi.org/10.1117/12.3040154
Primary Topic
Photoacoustic and Ultrasonic Imaging
Type
article
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article

Mid-infrared photoacoustic spectroscopy detecting continuous ultrasound for non-invasive tissue component analysis (Conference Presentation)

Saiko Kino, Yuji Matsuura, Kiiko Aiba
Photoacoustic and Ultrasonic Imaging
article

Mid-infrared photoacoustic spectroscopy detecting continuous ultrasound for non-invasive tissue component analysis (Conference Presentation)

Saiko Kino, Yuji Matsuura, Kiiko Aiba
article en

Abstract

Photoacoustic spectroscopy using mid-infrared light enables non-invasive analysis of biological tissue components. In photoacoustic spectroscopy, which detects ultrasonic waves generated by irradiation with pulsed infrared light, a method of inducing resonance by varying the pulse modulation frequency was investigated. This method was used to obtain photoacoustic spectra of human skin. Pre- and post-prandial measurements were performed over several days to investigate the feasibility of analysing blood components. The results showed that changes in measurement site, shape and daily baseline made the analysis of blood components difficult. Therefore, an investigation to reduce spectral variability is also being carried out.

Tohoku University (JP)
Zero hunger
Openalex Percentile: Top 95%
Photoacoustic and Ultrasonic Imaging
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