High throughput microscope on a chip for liquid biopsy assisted by artificial intelligence (Conference Presentation)

Temporal resolution is a key aspect to consider when choosing an imaging technique as it enables the observation of fast dynamics or high throughput imaging if combined with microfluidic channels for sample delivery. In this work we present a microscope on a chip for rare cell imaging that can be used for liquid biopsy applications. Using a pulsed laser as illumination source, 3D integrated optical circuits and fiber-based delay lines, we have demonstrated image acquisition with nanoseconds temporal resolution. This novel integrated approach guarantees ease of use, stable image quality and measurements automation.