Stability and Compatibility of Amikacin and Its Combination Antibiotics in 7.5% Icodextrin Peritoneal Dialysis Solution

Ciprofloxacin, amikacin, as well as combinations of amikacin and vancomycin, amikacin and cefazolin, amikacin and ciprofloxacin, can be added to icodextrin solution for treatment of PD-associated peritonitis because they maintain stability for a minimum of 7 days at the temperatures of 4°C and 25°C, and 8 h at 37°C.

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Publication Details

Journal
Blood Purification
Published
2025-03-20
DOI
https://doi.org/10.1159/000545085
Primary Topic
Antibiotics Pharmacokinetics and Efficacy
Type
article
Field-Weighted Citation Impact
0.00
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article

Stability and Compatibility of Amikacin and Its Combination Antibiotics in 7.5% Icodextrin Peritoneal Dialysis Solution

Qunying Guo, Haiping Mao, Pengchao Fang, Wei Chen et al.
Blood Purification
Antibiotics Pharmacokinetics and Efficacy
article

Stability and Compatibility of Amikacin and Its Combination Antibiotics in 7.5% Icodextrin Peritoneal Dialysis Solution

Qunying Guo, Haiping Mao, Pengchao Fang, Wei Chen, Zhihao Liu, Xiao Yang, Haishan Wu, Haiyan Hu
article en

Abstract

Ciprofloxacin, amikacin, as well as combinations of amikacin and vancomycin, amikacin and cefazolin, amikacin and ciprofloxacin, can be added to icodextrin solution for treatment of PD-associated peritonitis because they maintain stability for a minimum of 7 days at the temperatures of 4°C and 25°C, and 8 h at 37°C.

Blood PurificationVol. 54(4-5)
Sun Yat-sen University (CN), The First Affiliated Hospital, Sun Yat-sen University (CN), Ministry of Health (TT)
Openalex Percentile: Top 94%
Antibiotics Pharmacokinetics and Efficacy
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