A new isolation of vincamajine from <i>Vinca difformis</i> subsp. <i>sardoa</i> Stearn

The continuation of the phytochemical analysis to determine the alkaloid content of <i>Vinca difformis</i> subsp. <i>sardoa</i> Stearn, led to the isolation of the further compound vincamajine (<b>1</b>) which was reported from the species for the first time during this study. Its structure was established by means of extensive NMR, IR and MS analyses which are completely reported in this paper for the first time. In addition, the first chemophenetic evaluation about this compound was also carried out evidencing some important results which were fully described and discussed in this paper.

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Journal
Natural Product Research
Published
2025-03-20
DOI
https://doi.org/10.1080/14786419.2025.2477219
Primary Topic
Alkaloids: synthesis and pharmacology
Type
article
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article

A new isolation of vincamajine from Vinca difformis subsp. sardoa Stearn

Luigi Scipione, Ilaria Serafini, Paola Di Matteo, Fabio Sciubba et al.
Natural Product Research
Alkaloids: synthesis and pharmacology
article

A new isolation of vincamajine from Vinca difformis subsp. sardoa Stearn

Luigi Scipione, Ilaria Serafini, Paola Di Matteo, Fabio Sciubba, Daniela De Vita, Claudio Frezza, Rita Petrucci, Elisa Mastellone
article en

Abstract

The continuation of the phytochemical analysis to determine the alkaloid content of <i>Vinca difformis</i> subsp. <i>sardoa</i> Stearn, led to the isolation of the further compound vincamajine (<b>1</b>) which was reported from the species for the first time during this study. Its structure was established by means of extensive NMR, IR and MS analyses which are completely reported in this paper for the first time. In addition, the first chemophenetic evaluation about this compound was also carried out evidencing some important results which were fully described and discussed in this paper.

Natural Product ResearchVol. 40(3)
Link Campus University (IT), Sapienza University of Rome (IT)
Life in Land
Openalex Percentile: Top 93%
Alkaloids: synthesis and pharmacology
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A new isolation of vincamajine from <i>Vinca difformis</i> subsp. <i>sardoa</i> Stearn — Luigi Scipione, Ilaria Serafini, et al. · Natural Product Research (2025) | TGRS Research Map | TGRS