Abstract

Introduction:In patients under mechanical ventilatory support (MVA) the development of pulmonary hypertension (PHT) with mean pulmonary artery pressure (mPAP) > 20 mmHg and increased pulmonary vascular resistance (PVR) is a possibility.Objectives: General: To determine mean pulmonary artery pressure values and other hemodynamic variables using the Swan Ganz catheter.Specific: a) to correlate D-dimer levels and mean pulmonary artery pressure; b) to determine the relationship between mean pulmonary artery pressure, pulmonary vascular resistance and mortality.Material and Methods: Observational, descriptive, prospective, longitudinal study.It included 14 patients of both sexes between 18 and 80 years old, who were admitted to the ICU of the Hospital Nacional de Clnicas with need of invasive mechanical ventilation and right catheterization between 2021 and 2023.Results: Fourteen patients were included.Fifty-seven percent were male.The mean age was 70.36 2.35 years.The main etiologies were: community pneumonia (21%), septic shock (14.29%) and subarachnoid hemorrhage (14.29%).AVM parameters: PC 13.6 0.9 cmH2O, FiO2 0.49 0.05 mmHg, PEEP 6.3 0.46 cmH2O.Hemodynamic measurements were PAPm 23.68 0.89 mmHg, Wedge 14.19 0.93 mmHg, PVR 1.49 0.18 uW and transpulmonary gradient (TPG) 9.55 0.72 mmHg.Some 92.86% had PAPm 20 mmHg.Wedge pressure (p < 0.00001) and GTP (p < 0.0001) were predictors of PHT.Significant differences were observed between D-dimer and PAPm levels (p < 0.001).Among the deceased, PAPm and PVR increased.Conclusions: PTH was observed with elevated PAPm, Wedge and GTP with increased levels of DD.Elevated PAPm and PVR were associated with higher mortality and longer stay in the ICU.