Snapshot multispectral cameras targeted for surgical vision (Conference Presentation)

Standard-of-care endoscopy and laparoscopy require multiple cameras to enable molecular imaging, leading to challenges of co- registration and overlay. To address this, we are developing a targeted biomedical imaging camera using custom multispectral filter arrays integrated onto image sensors. The design augments RGB-Bayer filters with biomarker-targeted sub-pixel narrowband filters, thereby maintaining white-light imaging while adding MSI contrast enhancement. Prototypes were characterised using standard colour and resolution charts, and their biomarker imaging capabilities tested using imaging tissue-mimicking phantoms containing blood of varied oxygenation and ICG dye. This sensor is being developed in parallel with in vivo hyperspectral endoscopy clinical studies.