Unveiling the Therapeutic Potential of Banxia Xiexin Decoction in Alzheimer’s Disease: Insights From Network Pharmacology and Experimental Validation
Through systematic data analysis and experimental validation, the therapeutic advantages and fundamental molecular mechanisms of BXD in treating AD were revealed. These findings underscore the promising prospects and compelling potential of BXD, which targets the PI3K/Akt signaling pathway and inflammation, apoptosis, as a therapeutic strategy for improving AD.
Authors
- Gaofeng Qin (ORCID: https://orcid.org/0000-0001-6482-4242)
- Chen Li (ORCID: https://orcid.org/0000-0002-1560-7556)
- Bao‐liang Sun (ORCID: https://orcid.org/0000-0002-5178-1754)
- Wentao Wang (ORCID: https://orcid.org/0000-0003-3913-4455)
- Dan Wang (ORCID: https://orcid.org/0000-0001-5131-9351)
- Juanjuan Dai
- Rui Song (ORCID: https://orcid.org/0000-0002-4119-4433)
- Jingyi Sun (ORCID: https://orcid.org/0000-0003-3618-289X)
- Fantao Meng (ORCID: https://orcid.org/0000-0001-7996-0298)
- Zhe Liu (ORCID: https://orcid.org/0009-0004-1429-9207)
Institutions
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/dddt.s499852
- Citations
- 2
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 3.01