Sustained release of cytokines from migrasomes
Cytokines are released by cells in response to infections and tissue damage. A recent paper by Jiao <i>et al</i>. demonstrates that circulating monocytes release the cytokines tumor necrosis factor and Interleukin-6 encapsulated in large extracellular vesicles called migrasomes, from which the cytokines are secreted locally in a sustained fashion.
Authors
- Harald Stenmark (ORCID: https://orcid.org/0000-0002-1971-4252)
- Yan Zhen (ORCID: https://orcid.org/0000-0002-1999-8451)
Institutions
- Oslo University Hospital (NO)
- University of Oslo (NO)
Publication Details
- Journal
- Extracellular Vesicles and Circulating Nucleic Acids
- Published
- 2025-03-20
- DOI
- https://doi.org/10.20517/evcna.2025.15
- Citations
- 3
- Primary Topic
- Cellular transport and secretion
- Type
- article
- Field-Weighted Citation Impact
- 3.45