Extracellular(Serum) Levels of Matrix Metalloproteinases in Pediatric Type 1 Diabetes Mellitus and Association with Diabetic Ketoacidosis and Cerebral Edema
The distinct patterns of MMP-3 and MMP-9 elevations in DKACE highlight their potential as biomarkers for identifying and monitoring severe DKA complications. The findings suggest these enzymes play a significant role in cerebral edema pathophysiology, making them viable targets for future therapeutic interventions.
Authors
- Qingbo Xu (ORCID: https://orcid.org/0000-0003-2474-8155)
- Luxi Yang (ORCID: https://orcid.org/0009-0007-7773-9646)
- Qiang Huang (ORCID: https://orcid.org/0000-0002-7162-1221)
- Yinan Feng
- Liling Xie
- Yang Yu (ORCID: https://orcid.org/0000-0001-6584-4050)
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Jiangxi Provincial Children's Hospital (CN)
Publication Details
- Journal
- Diabetes Metabolic Syndrome and Obesity
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/dmso.s507337
- Citations
- 2
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.63
Funders
- Health Commission of Jiangxi Province