Resolvin D1 accelerates resolution of neuroinflammation by inhibiting microglia activation through the BDNF/TrkB signaling pathway
RvD1 alleviates neuropathic pain by reducing neuroinflammation through the ALX/FPR2 receptor and suppressing BDNF/TrkB signaling. These findings suggest RvD1 as a promising therapeutic agent for neuropathic pain management.
Authors
- Cunju Bo
- Xiaoming Liu (ORCID: https://orcid.org/0000-0003-0230-2742)
- Lingjun Xu
- Yongjian Liu (ORCID: https://orcid.org/0000-0002-0806-1671)
- Qiaodong Huang
Institutions
- Jinan University (CN)
- Guangdong Provincial People's Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-03-20
- DOI
- https://doi.org/10.1186/s40001-025-02424-7
- Citations
- 7
- Primary Topic
- Calpain Protease Function and Regulation
- Type
- article
- Field-Weighted Citation Impact
- 8.06