An Imported Case of Gigantic Amoebic Liver Abscess in a 24‐Year‐Old Woman in Singapore

A liver abscess can be due to several different microbiological aetiologies. While pyogenic liver abscess is most frequently encountered, amoebic liver abscess and hydatid cyst caused by the parasites, <i>Entamoeba histolytica</i> and <i>Echinococcus granulosus,</i> respectively, should be considered whenever there is epidemiological exposure. As parasitic infections are now rarely seen in clinical practice in developed countries with improvement in sanitation, lack of clinical experience in managing amoebic liver abscesses and overlapping clinical and imaging features between amoebic and pyogenic liver abscesses may lead to delay in diagnosis. In particular, although amoebic liver abscesses respond well to treatment if diagnosed early, they can progress and rupture with high mortality if treatment is delayed. Hence, early diagnosis and prompt initiation of antimicrobials are crucial to prevent complications and death. This case report highlights a case of a very large 21 cm ALA in a young lady to illustrate the challenges faced during diagnostic evaluation.

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Publication Details

Journal
Case Reports in Infectious Diseases
Published
2025-01-01
DOI
https://doi.org/10.1155/crdi/6230349
Primary Topic
Amoebic Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

An Imported Case of Gigantic Amoebic Liver Abscess in a 24‐Year‐Old Woman in Singapore

Jean‐Marc Chavatte, Edwin Chong Yu Sng
Case Reports in Infectious Diseases
Amoebic Infections and Treatments
article

An Imported Case of Gigantic Amoebic Liver Abscess in a 24‐Year‐Old Woman in Singapore

Jean‐Marc Chavatte, Edwin Chong Yu Sng
article en

Abstract

A liver abscess can be due to several different microbiological aetiologies. While pyogenic liver abscess is most frequently encountered, amoebic liver abscess and hydatid cyst caused by the parasites, <i>Entamoeba histolytica</i> and <i>Echinococcus granulosus,</i> respectively, should be considered whenever there is epidemiological exposure. As parasitic infections are now rarely seen in clinical practice in developed countries with improvement in sanitation, lack of clinical experience in managing amoebic liver abscesses and overlapping clinical and imaging features between amoebic and pyogenic liver abscesses may lead to delay in diagnosis. In particular, although amoebic liver abscesses respond well to treatment if diagnosed early, they can progress and rupture with high mortality if treatment is delayed. Hence, early diagnosis and prompt initiation of antimicrobials are crucial to prevent complications and death. This case report highlights a case of a very large 21 cm ALA in a young lady to illustrate the challenges faced during diagnostic evaluation.

Case Reports in Infectious DiseasesVol. 2025(1)
Ministry of Health (SG), Changi General Hospital (SG), National Centre for Infectious Diseases (SG)
Changi General Hospital
Good health and well-being
Openalex Percentile: Top 92%
Amoebic Infections and Treatments
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