Histopathological composition of thrombus material in a large cohort of patients with acute ischemic stroke: a study of atypical clots
Diabetes and TICA occlusion were the strongest predictors of atypical clot composition. We also observed a significant association between atypical composition and an increased number of passes. Furthermore, the presence of NETs in all thrombi analyzed, regardless of their composition, indicates inflammatory mechanisms associated with clot formation and consolidation in AIS.
Authors
- Francisco Hernández‐Fernández (ORCID: https://orcid.org/0000-0001-6681-2683)
- Tomás Segura (ORCID: https://orcid.org/0000-0003-3625-0987)
- Laura Restrepo Carvajal
- Gemma Serrano‐Heras (ORCID: https://orcid.org/0000-0001-9368-4832)
- Óscar Ayo‐Martín (ORCID: https://orcid.org/0000-0002-3632-1696)
- María Payá (ORCID: https://orcid.org/0000-0001-6045-7131)
- María José Pedrosa-Jiménez
- Ángela Fernández López
- Rosa Angélica Barbella-Aponte (ORCID: https://orcid.org/0000-0001-7757-9709)
- Laura Rojas-Bartolomé (ORCID: https://orcid.org/0000-0001-8089-550X)
- Enrique Juliá-Molla
- Jorge García‐García (ORCID: https://orcid.org/0000-0001-9867-9709)
- Lorena López-Martínez (ORCID: https://orcid.org/0000-0002-8040-1079)
- Juan David Molina‐Nuevo (ORCID: https://orcid.org/0000-0002-0516-1490)
Institutions
- Hospital General Universitario de Albacete (ES)
- University of Castilla-La Mancha (ES)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-03-20
- DOI
- https://doi.org/10.3389/fneur.2025.1563371
- Citations
- 2
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 2.71