Risk of Antipsychotic Initiation Among Older Dementia Patients Initiating Cholinesterase Inhibitors

This study found that rivastigmine users were more likely to initiate antipsychotics compared to donepezil users, while no significant difference between galantamine and donepezil users was observed. These findings emphasize the importance of careful medication monitoring and management to prevent prescribing cascades and reduce related adverse effects in dementia patients.

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Publication Details

Journal
Drug Healthcare and Patient Safety
Published
2025-03-01
DOI
https://doi.org/10.2147/dhps.s506523
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Risk of Antipsychotic Initiation Among Older Dementia Patients Initiating Cholinesterase Inhibitors

Rajender R. Aparasu, Jieni Li, Soumya Chikermane
Drug Healthcare and Patient Safety
Dementia and Cognitive Impairment Research
article

Risk of Antipsychotic Initiation Among Older Dementia Patients Initiating Cholinesterase Inhibitors

Rajender R. Aparasu, Jieni Li, Soumya Chikermane
article en

Abstract

This study found that rivastigmine users were more likely to initiate antipsychotics compared to donepezil users, while no significant difference between galantamine and donepezil users was observed. These findings emphasize the importance of careful medication monitoring and management to prevent prescribing cascades and reduce related adverse effects in dementia patients.

Drug Healthcare and Patient SafetyVol. Volume 17
University of Houston (US)
Good health and well-being
Openalex Percentile: Top 93%
Dementia and Cognitive Impairment Research
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