The efficacy of polymyxin B in treating stroke-associated pneumonia with carbapenem-resistant Gram-negative bacteria infections: a multicenter real-world study using propensity score matching
Combined inhalation of PMB demonstrated superior effectiveness in microbial clearance compared to non-combined inhalation in treating CR-GNB-infected SAP patients. We recommend aerosol combined inhalation of PMB and suggest developing personalized PMB-based regimens for individual patients to enhance treatment outcomes.
Authors
- Jian Qu (ORCID: https://orcid.org/0000-0002-6694-2450)
- Wen-Ming Long
- Qin Hu (ORCID: https://orcid.org/0000-0002-5910-7596)
- Ying Chen (ORCID: https://orcid.org/0000-0002-6412-0568)
- Qing Wan (ORCID: https://orcid.org/0000-0001-5234-9456)
- Wei-Xin Xu
- Qiang Qu (ORCID: https://orcid.org/0000-0002-1661-3261)
- Hainan Zhang (ORCID: https://orcid.org/0000-0002-1058-0462)
- Tiantian Xu (ORCID: https://orcid.org/0000-0002-9175-3264)
- Qihua Chen (ORCID: https://orcid.org/0000-0003-1826-3709)
- Haihui Zhuang
- Xiaoli Wu (ORCID: https://orcid.org/0009-0003-9821-898X)
- Yue Luo
- Wei J. Wang (ORCID: https://orcid.org/0000-0002-4848-7394)
Institutions
- Central South University (CN)
- Nanchang University (CN)
- Changsha Medical University (CN)
- Xuzhou Medical College (CN)
- Wuhan University (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Second People’s Hospital of Huai’an (CN)
- Renmin Hospital of Wuhan University (CN)
- Liuyang City Maternal and Child Health Hospital (CN)
- Second Xiangya Hospital of Central South University (CN)
- Xiangya Hospital Central South University (CN)
- First Affiliated Hospital of Nanchang University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-20
- DOI
- https://doi.org/10.3389/fphar.2025.1413563
- Citations
- 12
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 7.09