Clinical Hemophagocytic Lymphohistiocytosis (HLH): A Case Series

Hemophagocytic lymphohistiocytosis (HLH) is a rare but life-threatening hyperinflammatory syndrome characterized by excessive immune activation. Despite being historically associated with pediatric populations, HLH is increasingly recognized in adults, albeit with diagnostic and therapeutic challenges. This case series evaluates seven adult patients diagnosed with HLH, exploring their clinical presentation, diagnostic challenges, and treatment outcomes. Our findings highlight the need for improved awareness, timely diagnosis, and a tailored approach to managing adult HLH.