Multimodal Activity of a Novel Compound against Prostate and Pancreatic Cancer
These findings suggest that compound 5b holds promise for further development as a therapeutic option for prostate and pancreatic cancers. Its multimodal activity profile, targeting cell viability, migration, cell cycle progression, and cell death, warrants further investigation.
Authors
- Moacyr Jesus Barreto de Melo Rêgo (ORCID: https://orcid.org/0000-0002-1883-6012)
- Eduardo Davi Lima da Silva (ORCID: https://orcid.org/0000-0002-9926-1387)
- Joelson Germano Crispim (ORCID: https://orcid.org/0000-0002-3057-1299)
- Arsênio Rodrigues Oliveira (ORCID: https://orcid.org/0000-0001-9836-9161)
- Flaviana Alves dos Santos (ORCID: https://orcid.org/0000-0002-3189-1526)
- Michelly Cristiny Pereira (ORCID: https://orcid.org/0000-0002-1672-8202)
- Aldilane Gonçalves da Fonseca (ORCID: https://orcid.org/0000-0002-6366-9081)
- Ana Cristina Lima Leite (ORCID: https://orcid.org/0000-0002-9346-2292)
- Telma Maria Araújo Moura Lemos (ORCID: https://orcid.org/0000-0001-7118-2145)
- Maíra Galdino da Rocha Pitta (ORCID: https://orcid.org/0000-0001-5881-0338)
- Michelle Melgarejo da Rosa (ORCID: https://orcid.org/0000-0002-0163-3833)
- Ivan Rocha Pitta
Institutions
- Universidade Federal de Pernambuco (BR)
- Universidade Federal do Rio Grande do Norte (BR)
Publication Details
- Journal
- Current Topics in Medicinal Chemistry
- Published
- 2025-03-20
- DOI
- https://doi.org/10.2174/0115680266351687250309020134
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00