STUMP- A Challenging Differential Diagnosis and Therapeutic Dilemma

Smooth Muscle Tumor of Uncertain Malignant Potential (STUMP) refers to a diverse group of uterine neoplasms that do not fully meet the histologic criteria for classification as either benign or malignant tumors. Typically, when a uterine leiomyoma cannot be definitively classified as a standard or variant leiomyoma, adenomyoma, or leiomyosarcoma, it is categorized as a uterine smooth muscle tumor of uncertain malignant potential (STUMP). In our case 20 year nulligravida presented to gynae OPD with heavy menstruation with per abdomen mass of 30 weeks size. Ultrasound showed multiple uterine mass and patient was taken up for myomectomy.Histopathological report showed features suggestive of leiomyosarcoma and second opinion was taken which was suggestive of STUMP. In this case report, we summarize the current state of knowledge about uterine STUMP, with a particular focus on fertility sparing surgeries. The very purpose of reporting this case is to emphasize that STUMP mimicking leiomyosarcoma can affect a very young age girl. With premenopausal age, decision for hysterectomy is easy whereas in a young girl going ahead with hysterectomy is a crucial decision.No doubt it is a multidisciplinary approach with complete patient involvement who needs to be on regular close follow up.

Authors

Publication Details

Journal
Annals of Clinical and Medical Case Reports
Published
2025-01-01
DOI
https://doi.org/10.47829/acmcr.2025.141107
Primary Topic
Hematological disorders and diagnostics
Type
article
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article

STUMP- A Challenging Differential Diagnosis and Therapeutic Dilemma

Ananya Das, Yookarin Khonglah, Megha Goyal, Donbok Lynser et al.
Annals of Clinical and Medical Case Reports
Hematological disorders and diagnostics
article

STUMP- A Challenging Differential Diagnosis and Therapeutic Dilemma

Ananya Das, Yookarin Khonglah, Megha Goyal, Donbok Lynser, Birangana, Rimabati
article en

Abstract

Smooth Muscle Tumor of Uncertain Malignant Potential (STUMP) refers to a diverse group of uterine neoplasms that do not fully meet the histologic criteria for classification as either benign or malignant tumors. Typically, when a uterine leiomyoma cannot be definitively classified as a standard or variant leiomyoma, adenomyoma, or leiomyosarcoma, it is categorized as a uterine smooth muscle tumor of uncertain malignant potential (STUMP). In our case 20 year nulligravida presented to gynae OPD with heavy menstruation with per abdomen mass of 30 weeks size. Ultrasound showed multiple uterine mass and patient was taken up for myomectomy.Histopathological report showed features suggestive of leiomyosarcoma and second opinion was taken which was suggestive of STUMP. In this case report, we summarize the current state of knowledge about uterine STUMP, with a particular focus on fertility sparing surgeries. The very purpose of reporting this case is to emphasize that STUMP mimicking leiomyosarcoma can affect a very young age girl. With premenopausal age, decision for hysterectomy is easy whereas in a young girl going ahead with hysterectomy is a crucial decision.No doubt it is a multidisciplinary approach with complete patient involvement who needs to be on regular close follow up.

Annals of Clinical and Medical Case ReportsVol. 14(11)
Openalex Percentile: Top 91%
Hematological disorders and diagnostics
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STUMP- A Challenging Differential Diagnosis and Therapeutic Dilemma — Ananya Das, Yookarin Khonglah, et al. · Annals of Clinical and Medical Case Reports (2025) | TGRS Research Map | TGRS