Malignant hypertension, and if it was scleroderma? Lessons from two cases

<b>Key findings :</b> These cases underscore the importance of early detection of hematuria and autoimmune markers to expedite diagnosis of SRC in case of MHT. When SRC is suspected, high-dose angiotensin-converting enzyme inhibitors (ACEi) should be initiated immediately, even before biopsy confirmation and continued despite initial kidney function decline. Early intervention is crucial for optimising kidney outcomes and achieving effective blood pressure control.

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Publication Details

Journal
Blood Pressure
Published
2025-03-20
DOI
https://doi.org/10.1080/08037051.2025.2482741
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Malignant hypertension, and if it was scleroderma? Lessons from two cases

Etienne Cellot, B. Franko, Diane Giovannini, Sandra Jost et al.
Blood Pressure
Systemic Sclerosis and Related Diseases
article

Malignant hypertension, and if it was scleroderma? Lessons from two cases

Etienne Cellot, B. Franko, Diane Giovannini, Sandra Jost, Réda Laamech
article en

Abstract

<b>Key findings :</b> These cases underscore the importance of early detection of hematuria and autoimmune markers to expedite diagnosis of SRC in case of MHT. When SRC is suspected, high-dose angiotensin-converting enzyme inhibitors (ACEi) should be initiated immediately, even before biopsy confirmation and continued despite initial kidney function decline. Early intervention is crucial for optimising kidney outcomes and achieving effective blood pressure control.

Blood PressureVol. 34(1)
Centre Hospitalier Universitaire de Grenoble (FR), Centre Hospitalier Annecy Genevois (FR)
Zero hunger
Openalex Percentile: Top 93%
Systemic Sclerosis and Related Diseases
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