The Microbiota: Impact and Interconnections for a Good Sleep
Sleep is a cornerstone of human health, intricately regulated by neurological processes and profoundly influenced by the gut microbiota [1]. The interplay between these systems is dynamic, and the quality of our sleep can be a reflection of both brain and intestinal health. This article explores the interconnected roles of neurotransmitters, microbiota, and sleep cycles, offering insights into their mechanisms and implications for health.Sleep disorders, which affect approximately 15% of the population, are not merely an inconvenience but a significant health concern. They are more than just a symptom; they can serve as an early indicator of neurological and psychiatric conditions. The prevalence of sleep disturbances in children is alarmingly high, especially among those with conditions such as epilepsy and autism spectrum disorder (ASD). These disturbances have profound implications, from behavioral issues in children to the increased risk of accidents in adolescents.Understanding the biological underpinnings of sleep and its disturbances is critical. By examining the role of the microbiota, we gain a new perspective on how intestinal health influences sleep and vice versa. This relationship is not just theoretical; it has practical applications for improving sleep quality and overall well-being.
Authors
- Silvia Marino (ORCID: https://orcid.org/0000-0002-9612-2883)
- Éric Campo (ORCID: https://orcid.org/0000-0001-7647-8498)
- Giovanni Cacciaguerra (ORCID: https://orcid.org/0000-0002-8909-3498)
- Raffaele Falsaperla (ORCID: https://orcid.org/0000-0002-4482-3506)
- Amanda Maccarrone (ORCID: https://orcid.org/0009-0001-9483-9661)
- Piero Pavone (ORCID: https://orcid.org/0000-0002-5600-9560)
- Chiara Nannola
- Paolo Mainardi
Publication Details
- Journal
- Japanese Journal of Gastroenterology and Hepatology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.47829/jjgh.2025.101406
- Citations
- 1
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.58