The Effect of glycocholic acid on the growth, membrane permeability, conjugation and antibiotic susceptibility of Enterobacteriaceae
Overall, these findings broaden the current understanding about bile resistance of Gram-negative bacteria and suggest that GCA can be used to inhibit bacterial growth, augment the activity of antimicrobial compounds and diminish acquisition and dissemination of antibiotic resistance genes by conjugation.
Authors
- Boris Fichtman
- Ohad Gal‐Mor (ORCID: https://orcid.org/0000-0002-2540-6790)
- Bar Piscon
- Amos Adler (ORCID: https://orcid.org/0000-0003-2957-9741)
- Galia Rahav (ORCID: https://orcid.org/0000-0003-4039-0958)
- Amnon Harel (ORCID: https://orcid.org/0000-0003-4230-7468)
Institutions
- Bar-Ilan University (IL)
- Tel Aviv University (IL)
- Tel Aviv Sourasky Medical Center (IL)
- Sheba Medical Center (IL)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-03-20
- DOI
- https://doi.org/10.3389/fcimb.2025.1550545
- Citations
- 2
- Primary Topic
- Drug Transport and Resistance Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 2.09