Kidney Damage Secondary to Iodinated Contrast Products: 46 Cases in Mali

Introduction: The number of patients undergoing radiological interventions with injection of iodinated contrast media (PCI) to arrive at a diagnosis is increasing. Prophylaxis of nephropathy with iodinated contrast media (NPCI) is therefore important. AKI (acute renal failure), in the context of NPCI is defined by an increase of 25% or more of 44umol/ in plasma creatinine concentrations compared to the initial values and typically occurs within 3 days after the injection of iodinated product in the absence of other etiologies. The objective of our work was to define the epidemiological, clinical, biological and evolutionary characteristics of nephropathy induced by iodinated contrast media. Material and Methods: This was a cross-sectional, retrospective study, extending over a period of 5 years in the nephrology department of the CHU du point ‘’G’’. Were included in our study, all patients who had been received in the department for impaired renal function and who had previously undergone a CT scan. The parameters studied were the epidemiological characteristics, clinical and paraclinical data. Results: Our study involved 46 patients out of a total of 3420 patients admitted to the department for chronic renal failure, i.e. a frequency of 1.34% of cases. The average age of our patients was 53.5 years with extremes ranging from 22 to 85 years. A male predominance was noted with 29 men against 17 women with a sex ratio = 1.70. End-stage chronic renal failure (ERF) represented the majority of our patients in 15 cases, followed by early ERF in 11 cases and moderate ERF in 10 cases. High blood pressure (HBP) was the most common comorbidity in our series, i.e. 24 cases, followed by diabetes in 3 cases. In our series, cerebral CT angiography was the most commonly performed examination in 15 cases, followed by uro-CT in 11 cases and abdominal CT angiography in 10 cases. Conclusion: Nephropathy induced by iodinated contrast media is thought to be due to vasoconstriction, ...