Management approaches for primary hepatic lymphoma: 10 year institutional experience with comprehensive literature review

PHL are an extremely rare subtype of NHL for which there is no clear treatment consensus. Primary hepatic DLBCL appears to be treated mostly with chemotherapy with good disease control. For indolent PHL, low-dose RT appears to have good overall disease control with minimal toxicity. Our RT data is limited by the short duration of follow-up for patients receiving RT compared to those who received chemotherapy, surgery or observation. However, our results are encouraging for the use of RT for appropriate patients with indolent PHL.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-03-20
DOI
https://doi.org/10.3389/fonc.2025.1475118
Citations
2
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
2.94
Controls
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article

Management approaches for primary hepatic lymphoma: 10 year institutional experience with comprehensive literature review

Neil Ari Wijetunga, Brandon S. Imber, J El-Khoury, Jennifer Ma et al.
2 citations
Frontiers in Oncology
Lymphoma Diagnosis and Treatment
2.94
article

Management approaches for primary hepatic lymphoma: 10 year institutional experience with comprehensive literature review

Neil Ari Wijetunga, Brandon S. Imber, J El-Khoury, Jennifer Ma, Beatrice Fregonese, Rémy Daou, Joachim Yahalom, Carla Hajj, Josiane Bou Eid
article en
2 citations

Abstract

PHL are an extremely rare subtype of NHL for which there is no clear treatment consensus. Primary hepatic DLBCL appears to be treated mostly with chemotherapy with good disease control. For indolent PHL, low-dose RT appears to have good overall disease control with minimal toxicity. Our RT data is limited by the short duration of follow-up for patients receiving RT compared to those who received chemotherapy, surgery or observation. However, our results are encouraging for the use of RT for appropriate patients with indolent PHL.

Frontiers in OncologyVol. 15
University of North Carolina at Chapel Hill (US), Memorial Sloan Kettering Cancer Center (US), Saint Joseph University (LB)
Quality Education
Openalex Percentile: Top 11%
Lymphoma Diagnosis and Treatment
2.94
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