[MSB-33] Postoperative Early- to Mid-Term Results of the Ozaki Procedure Applied to Aortic Valve Pathologies

Objective: This study aimed to evaluate our early- to mid-term results with the aortic valve neocuspidization technique (Ozaki procedure) in aortic valve pathologies. METHOD: This study retrospectively examined the data of 243 patients (172 males, 71 females; mean age: 53.11±18.3 years; range, 17 to 82 years) who underwent the Ozaki procedure between February 2019 and August 2024. Results: The primary pathology was aortic insufficiency in 52 (21.3%) patients and aortic stenosis in 201 (82.7%) patients. The aortic valve morphology was trileaflet in 196 (80.6%) patients, bileaflet in 44 (18.1%) patients, unicuspid in two (0.8%) patients, and quadricuspid in one (0.4%) patient. Additional cardiac surgical procedures were performed on 99 (40.7%) patients. Preoperative echocardiographic findings in patients with aortic stenosis showed a peak gradient of 91.39±33.1 mmHg and a mean gradient of 54.9±18.3 mmHg. The mean cross-clamp time was 110.2±35.6 min, while the cardiopulmonary bypass time was 141.2±39.6 min. Postoperative echocardiographic findings showed significant improvement in peak and mean gradients at six months (18.3±6.2 and 8.9±2.4 mmHg) and one (15.6±5.7 and 8.7±3.5 mmHg), two (14.2±4.7 and 7.7±2.5 mmHg), three (13.69±3.8 and 6.4±3.7 mmHg), and four (12.4±3.8 and 6.3±2.4 mmHg) years. Conclusion: Aortic valve neocuspidization is a viable technique for all aortic pathologies. It offers advantages such as achieving good hemodynamics postoperatively, avoiding anticoagulant medications, and allowing additional surgical procedures.