Structural Changes in Membrane Dynamics under the Action of Miltefosine
Miltefosine induces a decrease in membrane fluidity of cancer cells, and this effect was related to decreased cell viability and total cholesterol levels. Miltefosine may be an effective antitumor agent and has great potential as an adjuvant therapy in the future.
Authors
- Irina Georgieva (ORCID: https://orcid.org/0000-0002-1458-2457)
- Sonia Apostolova (ORCID: https://orcid.org/0000-0003-2054-0533)
- Rumiana Tzoneva (ORCID: https://orcid.org/0000-0001-6659-2588)
- Teodora Vukova
- Kostadin Rangelov Kostadinov (ORCID: https://orcid.org/0000-0003-1414-8738)
Institutions
- Bulgarian Academy of Sciences (BG)
- Institute of Biophysics (BG)
- Institute of Mechanics (BG)
Publication Details
- Journal
- Discovery Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.24976/discov.med.202537194.45
- Primary Topic
- Botanical Research and Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bulgarian Academy of Sciences