Research on the Antitumor Effects of -Glucan in the Gut

Intestinal tumors pose a significant threat to human health, and existing treatments have limitations, making the exploration of new therapeutic approaches highly important. -Glucan, a naturally occurring bioactive polysaccharide, has garnered significant interest in anti-tumor research. This paper, using literature review and case analysis methods, systematically elaborates on its mechanisms of action in combating intestinal tumors. -Glucan is widely sourced, structurally diverse, and possesses various physiological functions, such as immune regulation and anti-inflammatory effects. Its anti-tumor mechanisms primarily include: Immune modulation activating immune cells, it can trigger the apoptosis of tumor cells, restrain the proliferation of tumors, and prevent tumor metastasis. Modulating gut microbiota - encouraging the growth of beneficial bacteria while inhibiting harmful ones; its metabolic byproducts can also inhibit tumor growth. Clinical studies have shown that -glucan, when used alone, exhibits immune-regulatory and potential tumor-suppressive effects. Moreover, it can work synergistically with chemotherapeutic drugs to boost effectiveness, providing a new approach for the prevention as well as treatment of tumors in the intestine.