Stem Cell Usage in Dentistry: A Promising Future

Introduction: Stem cells are characterized by their ability to both regenerate themselves and develop into specialized cell types.They have the unique ability to self-renew and generate various cell types, offering innovative approaches for tissue regeneration and disease treatment.In dentistry, mesenchymal stem/stromal cells (MSCs) have been discovered in numerous oral and maxillofacial tissues, highlighting oral tissues as a plentiful reservoir of stem cells.These oral stem and mucosal cells are anticipated to serve as an excellent source for creating genetically reprogrammed cells, such as induced pluripotent stem (iPS) cells.Additionally, oral tissues are expected to function not only as a source but also as therapeutic targets for stem cell applications, as regenerative and tissue engineering therapies in dentistry gain growing clinical attention.General Information: Stem cells can be derived from various sources, including dental pulp, periodontal ligament, and even oral mucosa.Dental stem cells are especially attractive due to their proximity to the oral cavity and their ability to differentiate into a variety of tissue types such as dentin, bone, and nerve cells.The concept of regenerative dentistry is to use stem cells to regenerate or replace damaged oral tissues, offering patients a solution to conditions that were previously considered irreversible.While stem cell therapy in dentistry is still largely experimental, the ongoing advancements in the field are promising.