ACSL6-Mediated Cell Ferroptosis by Inhibiting AMPK Pathway in Periodontitis Stem Cells
The ferroptosis-related gene <i>ACSL6</i> was highly expressed in periodontitis tissues, and <i>ACSL6</i> silencing enhanced viability and inhibited ferroptosis in <i>P. gingivalis</i>-LPS-mediated hPDLFs by upregulating the AMPK pathway.
Authors
- LongHang Chou
- Ya‐Ting Chang (ORCID: https://orcid.org/0000-0003-2580-4622)
- Chongmai Zeng (ORCID: https://orcid.org/0000-0003-0325-6469)
- Peng Li (ORCID: https://orcid.org/0000-0002-3325-7262)
- Yeling Lu (ORCID: https://orcid.org/0000-0001-9934-1128)
- Orkideh Shafiee Allaf
- Yue Xu
Institutions
- Guangdong Province Stomatological Hospital (CN)
- Key Laboratory of Guangdong Province (CN)
- Stomatology Hospital (CN)
Publication Details
- Journal
- Discovery Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.24976/discov.med.202537194.43
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- National Natural Science Foundation of China