Reconstituted High-Density Lipoproteins Rescue Diabetes-Impaired Endothelial Cell Metabolic Reprograming and Angiogenic Responses to Hypoxia
The PDK4/PDC axis response to ischemia is impaired in diabetes and is important for the proangiogenic effects of rHDL.
Authors
- Peter J. Psaltis (ORCID: https://orcid.org/0000-0003-0222-5468)
- Lauren Sandeman (ORCID: https://orcid.org/0000-0001-7721-6879)
- Victoria Nankivell (ORCID: https://orcid.org/0000-0003-3842-9278)
- K. Primer (ORCID: https://orcid.org/0000-0003-2178-6607)
- Emma L. Solly (ORCID: https://orcid.org/0000-0001-9992-1181)
- Christina A. Bursill (ORCID: https://orcid.org/0000-0002-0682-8760)
- Liam Stretton (ORCID: https://orcid.org/0009-0004-5278-7260)
- Joanne T. M. Tan (ORCID: https://orcid.org/0000-0003-1875-4882)
Institutions
- Australian Research Council (AU)
- South Australian Health and Medical Research Institute (AU)
- The University of Adelaide (AU)
Publication Details
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Published
- 2025-03-20
- DOI
- https://doi.org/10.1161/atvbaha.124.320110
- Citations
- 2
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.87