Towards propagation of epidermal cells for wound repair: glass, as cell culture substrate, enhances proliferation and migration of human keratinocytes

Glass, as a culture substrate, promotes epidermal differentiation and enhances keratinocyte migration. The latter is a critical factor in re-epithelialization and wound healing. Functional properties suggest that glass may optimize the inflammatory response and promote efficient wound repair, making it a promising candidate for the short-term expansion of keratinocytes for transplantation purposes. Further <i>in-vivo</i> validation is required to definitively establish the efficacy of keratinocytes cultured on glass for clinical applications.

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Publication Details

Journal
Frontiers in Bioengineering and Biotechnology
Published
2025-03-20
DOI
https://doi.org/10.3389/fbioe.2025.1547044
Citations
1
Primary Topic
Wound Healing and Treatments
Type
article
Field-Weighted Citation Impact
1.03
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article

Towards propagation of epidermal cells for wound repair: glass, as cell culture substrate, enhances proliferation and migration of human keratinocytes

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1 citations
Frontiers in Bioengineering and Biotechnology
Wound Healing and Treatments
1.03
article

Towards propagation of epidermal cells for wound repair: glass, as cell culture substrate, enhances proliferation and migration of human keratinocytes

Hady Shahin, Ahmed T. El‐Serafi, Ingrid Steinvall, Folke Sjöberg, Moustafa Elmasry
article en
1 citations

Abstract

Glass, as a culture substrate, promotes epidermal differentiation and enhances keratinocyte migration. The latter is a critical factor in re-epithelialization and wound healing. Functional properties suggest that glass may optimize the inflammatory response and promote efficient wound repair, making it a promising candidate for the short-term expansion of keratinocytes for transplantation purposes. Further <i>in-vivo</i> validation is required to definitively establish the efficacy of keratinocytes cultured on glass for clinical applications.

Frontiers in Bioengineering and BiotechnologyVol. 13
Linköping University (SE), October University of Modern Sciences and Arts (EG)
Openalex Percentile: Top 24%
Wound Healing and Treatments
1.03
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