Towards propagation of epidermal cells for wound repair: glass, as cell culture substrate, enhances proliferation and migration of human keratinocytes
Glass, as a culture substrate, promotes epidermal differentiation and enhances keratinocyte migration. The latter is a critical factor in re-epithelialization and wound healing. Functional properties suggest that glass may optimize the inflammatory response and promote efficient wound repair, making it a promising candidate for the short-term expansion of keratinocytes for transplantation purposes. Further <i>in-vivo</i> validation is required to definitively establish the efficacy of keratinocytes cultured on glass for clinical applications.
Authors
- Hady Shahin (ORCID: https://orcid.org/0000-0003-3894-6849)
- Ahmed T. El‐Serafi (ORCID: https://orcid.org/0000-0001-5394-9082)
- Ingrid Steinvall (ORCID: https://orcid.org/0000-0002-8027-9632)
- Folke Sjöberg (ORCID: https://orcid.org/0000-0002-5903-2918)
- Moustafa Elmasry
Institutions
- Linköping University (SE)
- October University of Modern Sciences and Arts (EG)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-03-20
- DOI
- https://doi.org/10.3389/fbioe.2025.1547044
- Citations
- 1
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.03