Exploring sex differences in infective endocarditis – a prospective, observational study from Western Norway
Mitral valve IE was more common in females and strongly associated with higher mortality. Females with IE had higher mortality rates, more frequent mitral valve involvement, and a greater incidence of S. aureus infections. Despite the clear survival benefit of surgery, females with aortic valve IE underwent fewer and later surgeries. These findings highlight potential sex disparities in IE management and emphasize the need for further research into sex-based differences in treatment strategies and outcomes.
Authors
- Einar Skulstad Davidsen (ORCID: https://orcid.org/0000-0003-4600-2370)
- Helga Midtbø (ORCID: https://orcid.org/0000-0002-3558-9914)
- Øyvind Kommedal (ORCID: https://orcid.org/0000-0002-4390-0370)
- Pirjo‐Riitta Salminen
- Stina Jordal
- Rune Haaverstad (ORCID: https://orcid.org/0000-0002-3242-7602)
- Øystein Alexander Power
- Eli Leirdal Hoem
- Bård Reiakvam Kittang
Institutions
- Haukeland University Hospital (NO)
- Haraldsplass Diakonale Sykehus (NO)
- University of Bergen (NO)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2025-03-20
- DOI
- https://doi.org/10.1186/s12872-025-04631-w
- Citations
- 6
- Primary Topic
- Infective Endocarditis Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 8.13