Aberrant Hematopoiesis and <scp>CD8</scp><sup>+</sup> T‐Cell Activation in Thymoma‐Associated Pure Red Cell Aplasia
Thymoma-PRCA is associated with excessive CD8 + T-cell activation and an inflammatory bone marrow environment, leading to impaired erythropoiesis. These findings provide novel insights into the immune dysregulation underlying thymoma-associated PRCA and may help identify potential therapeutic targets.
Authors
- Xifeng Dong (ORCID: https://orcid.org/0000-0003-1278-129X)
- Liyan Yang (ORCID: https://orcid.org/0009-0004-5878-9363)
- Huaquan Wang (ORCID: https://orcid.org/0000-0003-2402-2717)
- Xiaoman He (ORCID: https://orcid.org/0000-0001-6662-9440)
- Yongfeng Liang (ORCID: https://orcid.org/0000-0002-7531-1108)
- Pu Tang (ORCID: https://orcid.org/0000-0003-2296-9544)
- Yumei Liu (ORCID: https://orcid.org/0000-0002-7344-2796)
- Huiqin Zhang (ORCID: https://orcid.org/0000-0002-0698-0252)
- Mengyuan Liu (ORCID: https://orcid.org/0000-0002-2315-7022)
- Yongxiang Wei (ORCID: https://orcid.org/0009-0002-4656-9289)
- Haiyue Niu (ORCID: https://orcid.org/0000-0002-9324-7699)
Institutions
- Capital Medical University (CN)
- Tianjin Medical University General Hospital (CN)
- Second Hospital of Tianjin Medical University (CN)
- Beijing Friendship Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Thoracic Cancer
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1111/1759-7714.70046
- Citations
- 4
- Primary Topic
- Myasthenia Gravis and Thymoma
- Type
- article
- Field-Weighted Citation Impact
- 5.56
Funders
- Tianjin Municipal Health Commission
- National Natural Science Foundation of China
- Tianjin Municipal Education Commission
- Tianjin Science and Technology Program