Nanocarrier-based Drug Delivery Systems: A Way to Effective Diabetes Management
Abstract Diabetes mellitus (DM) is a metabolic chronic disease distinguished by unexpectedly and inappropriately elevated levels of glucose in the blood of any individual. It has various categories depending on various causative agents or differences in the etiology of each class. Diabetes is regrettably one of the most prevalent diseases worldwide and continues to be the seventh leading cause of death in the USA. To overcome this chronic disease, significant work has been done through decades leading to various research, different management techniques and a majorly large amount of work has been done in the usage of nanotechnology. This initiative leads to the production of various formulations for the treatment of diabetes using nanotechnology. Examples of these products are insulin liposomes, insulin noisome, and gold or zinc oxide nanoparticles which show greater therapeutic efficacy and subsequently good control of DM, and these are also used for precise drug deliveries. This review covers the use of different types of nanoparticles for enhanced delivery of various hypoglycemic agents in comparison to traditional therapies. Many new research and studies about antidiabetic drugs and nanotechnology are still going on and would be so profitable in managing and treating DM.
Authors
- Rakesh K. Sindhu (ORCID: https://orcid.org/0000-0003-2619-4643)
- Marios Papadakis (ORCID: https://orcid.org/0000-0002-9020-874X)
- Najlaa H. Almohmadi (ORCID: https://orcid.org/0000-0002-1188-7036)
- M. Arockia Babu (ORCID: https://orcid.org/0000-0001-6547-1637)
- Ankita Tiwari (ORCID: https://orcid.org/0000-0002-0668-3645)
- Αθανάσιος Αλεξίου (ORCID: https://orcid.org/0000-0002-2206-7236)
- Asmaa S. A. Yassen (ORCID: https://orcid.org/0000-0002-7956-9739)
- Tushar Chaudhary
- Ekta Ekta
- Gaber El-Saber Batiha
Institutions
- Chandigarh University (IN)
- Suez Canal University (EG)
- Witten/Herdecke University (DE)
- Damanhour University (EG)
- Umm al-Qura University (SA)
- Barmherzige Schwestern Krankenhaus Wien (AT)
- Andalas University (ID)
- Sharda University (IN)
- GLA University (IN)
Publication Details
- Journal
- BioNanoScience
- Published
- 2025-03-20
- DOI
- https://doi.org/10.1007/s12668-025-01818-5
- Citations
- 4
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 2.39