Cancer Antigen 125 Levels at Time of Ovarian Cancer Diagnosis by Race and Ethnicity
In this cohort study of patients with ovarian cancer, American Indian and Black patients were 23% less likely to have an elevated CA-125 level at diagnosis. Current CA-125 thresholds may miss racially and ethnically diverse patients with ovarian cancer. Work is needed to develop inclusive CA-125 thresholds and diagnostic guidelines and not compound disparities in ovarian cancer diagnosis and treatment.
Authors
- Anna Jo Bodurtha Smith (ORCID: https://orcid.org/0000-0002-7692-773X)
- Emily Gleason (ORCID: https://orcid.org/0000-0003-4789-995X)
- Anne Marie McCarthy (ORCID: https://orcid.org/0000-0002-3068-2669)
- Elizabeth Amatruda Howell (ORCID: https://orcid.org/0009-0008-0048-411X)
- Xingmei Wang (ORCID: https://orcid.org/0000-0002-0281-0336)
- S Kadiyala
Institutions
- University of Pennsylvania Health System (US)
- Abramson Cancer Center (US)
- University of Pennsylvania (US)
- Philadelphia University (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-03-20
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.1292
- Citations
- 9
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 15.28