The Effects of Semaglutide on Inflammation and Immune Activation in HIV-associated Lipohypertrophy
In this randomized controlled trial of semaglutide in PWH, we report significant decreases in markers of inflammation that are associated with morbidity and mortality in this population. These results add to the growing literature demonstrating the anti-inflammatory effects of semaglutide. Further studies in PWH are warranted.
Authors
- Grace A. McComsey (ORCID: https://orcid.org/0000-0003-2690-8888)
- Kate Ailstock
- Nicholas Funderburg (ORCID: https://orcid.org/0000-0003-3113-1217)
- M.J. Cummings
- Allison Ross Eckard (ORCID: https://orcid.org/0000-0002-3069-7721)
- Abdus Sattar (ORCID: https://orcid.org/0000-0003-3863-3113)
- Qian Wu (ORCID: https://orcid.org/0000-0002-3550-7923)
- Danielle Labbato
Institutions
- Medical University of South Carolina (US)
- University Hospitals of Cleveland (US)
- Ohio Department of Health (US)
- The Ohio State University (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-03-20
- DOI
- https://doi.org/10.1093/ofid/ofaf152
- Citations
- 4
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 6.76