Lymphoepithelial cyst of the pancreatic tail: a rare entity with surgical and histopathological insights

Lymphoepithelial cysts (LECs) of the pancreas are rare, benign lesions often discovered incidentally during imaging for unrelated conditions. Their radiological features frequently overlap with those of other more common pancreatic cystic lesions, presenting a diagnostic challenge. In this report from a general surgical department on the Australia, we detail the assessment and management of a 54-year-old male with an enlarging pancreatic tail lesion initially thought to be a mucinous cystic neoplasm. Laparoscopic distal pancreatectomy and splenectomy was performed, and subsequent histopathological evaluation confirmed a benign LEC. This report reviews the literature base, clinical presentation, radiological findings, surgical approach, and pathological diagnosis of this rare condition. We emphasize the importance of a tailored approach to management and the role of surgery in definitive treatment.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-03-01
DOI
https://doi.org/10.1093/jscr/rjaf186
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
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article

Lymphoepithelial cyst of the pancreatic tail: a rare entity with surgical and histopathological insights

William Rumble, P. Martin
Journal of Surgical Case Reports
Pancreatic and Hepatic Oncology Research
article

Lymphoepithelial cyst of the pancreatic tail: a rare entity with surgical and histopathological insights

William Rumble, P. Martin
article en

Abstract

Lymphoepithelial cysts (LECs) of the pancreas are rare, benign lesions often discovered incidentally during imaging for unrelated conditions. Their radiological features frequently overlap with those of other more common pancreatic cystic lesions, presenting a diagnostic challenge. In this report from a general surgical department on the Australia, we detail the assessment and management of a 54-year-old male with an enlarging pancreatic tail lesion initially thought to be a mucinous cystic neoplasm. Laparoscopic distal pancreatectomy and splenectomy was performed, and subsequent histopathological evaluation confirmed a benign LEC. This report reviews the literature base, clinical presentation, radiological findings, surgical approach, and pathological diagnosis of this rare condition. We emphasize the importance of a tailored approach to management and the role of surgery in definitive treatment.

Journal of Surgical Case ReportsVol. 2025(3)
Sunshine Coast University Hospital (AU)
Good health and well-being
Openalex Percentile: Top 93%
Pancreatic and Hepatic Oncology Research
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Lymphoepithelial cyst of the pancreatic tail: a rare entity with surgical and histopathological insights — William Rumble, P. Martin · Journal of Surgical Case Reports (2025) | TGRS Research Map | TGRS