A simple way to well-posedness in H1 of a delay differential equation from cell biology
We present an application of recent well-posedness results in the theory of delay differential equations for ordinary differential equations [10] to a generalized population model for stem cell maturation. The weak approach using Sobolev-spaces we take allows for a larger class of initial prehistories and makes checking the requirements for well-posedness of such a model considerably easier compared to previous approaches. In fact the present approach is a possible means to guarantee that the solution manifold is not empty, which is a necessary requirement for a C 1 -approach to work.
Authors
- Marcus Waurick (ORCID: https://orcid.org/0000-0003-4498-3574)
- Bernhard Aigner (ORCID: https://orcid.org/0009-0009-8252-162X)
Institutions
- TU Bergakademie Freiberg (DE)
Publication Details
- Journal
- Journal of Differential Equations
- Published
- 2025-03-20
- DOI
- https://doi.org/10.1016/j.jde.2025.113241
- Citations
- 2
- Primary Topic
- Mathematical Biology Tumor Growth
- Type
- article
- Field-Weighted Citation Impact
- 2.74
Funders
- Freistaat Sachsen