A simple way to well-posedness in H1 of a delay differential equation from cell biology

We present an application of recent well-posedness results in the theory of delay differential equations for ordinary differential equations [10] to a generalized population model for stem cell maturation. The weak approach using Sobolev-spaces we take allows for a larger class of initial prehistories and makes checking the requirements for well-posedness of such a model considerably easier compared to previous approaches. In fact the present approach is a possible means to guarantee that the solution manifold is not empty, which is a necessary requirement for a C 1 -approach to work.

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Publication Details

Journal
Journal of Differential Equations
Published
2025-03-20
DOI
https://doi.org/10.1016/j.jde.2025.113241
Citations
2
Primary Topic
Mathematical Biology Tumor Growth
Type
article
Field-Weighted Citation Impact
2.74

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article

A simple way to well-posedness in H1 of a delay differential equation from cell biology

Marcus Waurick, Bernhard Aigner
2 citations
Journal of Differential Equations
Mathematical Biology Tumor Growth
2.74
article

A simple way to well-posedness in H1 of a delay differential equation from cell biology

Marcus Waurick, Bernhard Aigner
article en
2 citations

Abstract

We present an application of recent well-posedness results in the theory of delay differential equations for ordinary differential equations [10] to a generalized population model for stem cell maturation. The weak approach using Sobolev-spaces we take allows for a larger class of initial prehistories and makes checking the requirements for well-posedness of such a model considerably easier compared to previous approaches. In fact the present approach is a possible means to guarantee that the solution manifold is not empty, which is a necessary requirement for a C 1 -approach to work.

Journal of Differential EquationsVol. 435
TU Bergakademie Freiberg (DE)
Freistaat Sachsen
Openalex Percentile: Top 12%
Mathematical Biology Tumor Growth
2.74
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