Development of an optical sensor for real-time monitoring of hemodynamic parameters in ECMO settings (Conference Presentation)

Current extracorporeal membrane oxygenation (ECMO) systems are unable to provide long-term respiratory support for patients. Pulmonary assistant systems have been developed to enable permanent respiratory support overcoming the limitations of traditional ECMO. These devices require live feedback on the function of their gas exchangers and patient health metrics. Thus, we propose developing CW-NIRS sensors to extract whole blood oxygenation at the gas exchanger inlet and outlet and quantify total hemoglobin concentration in real-time. A calibration approach based on the ratio of the logarithms of light intensities was utilized to enable accurate measurements in whole blood. We present preliminary results of assessing the performance of this optical sensor using this calibration in an in-vitro setting.

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Published
2025-03-20
DOI
https://doi.org/10.1117/12.3042400
Primary Topic
Hemodynamic Monitoring and Therapy
Type
article
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article

Development of an optical sensor for real-time monitoring of hemodynamic parameters in ECMO settings (Conference Presentation)

Keith E. Cook, Jana M. Kainerstorfer, William B. Scammon, Osama Elgabori et al.
Hemodynamic Monitoring and Therapy
article

Development of an optical sensor for real-time monitoring of hemodynamic parameters in ECMO settings (Conference Presentation)

Keith E. Cook, Jana M. Kainerstorfer, William B. Scammon, Osama Elgabori, Kelly R. Strong
article en

Abstract

Current extracorporeal membrane oxygenation (ECMO) systems are unable to provide long-term respiratory support for patients. Pulmonary assistant systems have been developed to enable permanent respiratory support overcoming the limitations of traditional ECMO. These devices require live feedback on the function of their gas exchangers and patient health metrics. Thus, we propose developing CW-NIRS sensors to extract whole blood oxygenation at the gas exchanger inlet and outlet and quantify total hemoglobin concentration in real-time. A calibration approach based on the ratio of the logarithms of light intensities was utilized to enable accurate measurements in whole blood. We present preliminary results of assessing the performance of this optical sensor using this calibration in an in-vitro setting.

Carnegie Mellon University (US)
Affordable and clean energy
Openalex Percentile: Top 91%
Hemodynamic Monitoring and Therapy
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Development of an optical sensor for real-time monitoring of hemodynamic parameters in ECMO settings (Conference Presentation) — Keith E. Cook, Jana M. Kainerstorfer, et al. · (2025) | TGRS Research Map | TGRS