Independent and Combined Effects of Particulate Matter and Sleep Deprivation on Human Skin Barrier
PM exposure impaired skin barrier function, while short-term sleep deprivation alone did not significantly affect the barrier, either independently or in combination with PM. However, it was observed that the sleep deprivation-only, while not directly causing barrier damage, induced changes in ER stress-related gene expression in tape-stripped skin samples, like the PM exposure-only. This suggests that such signaling pathways could potentially exacerbate skin barrier deterioration.
Authors
- Il Joo Kwon (ORCID: https://orcid.org/0000-0003-1314-6829)
- Sang Ho Oh (ORCID: https://orcid.org/0000-0002-4477-1400)
- Shinwon Hwang (ORCID: https://orcid.org/0000-0002-0202-7800)
- Hye-Won Na (ORCID: https://orcid.org/0000-0002-5024-6100)
- Geunhyuk Jang (ORCID: https://orcid.org/0000-0003-0389-5105)
- Yu Jeong Bae (ORCID: https://orcid.org/0000-0001-8861-600X)
- Hae Kwang Lee (ORCID: https://orcid.org/0000-0001-8445-6889)
- Nari Cha
- Hyoung-June Kim (ORCID: https://orcid.org/0000-0003-0839-1264)
- Eun Jung Lee (ORCID: https://orcid.org/0000-0002-8401-2652)
- Ji Young Kim (ORCID: https://orcid.org/0000-0002-6217-321X)
- S. Y. Park (ORCID: https://orcid.org/0009-0003-6649-308X)
- Jung Hyang Park (ORCID: https://orcid.org/0000-0002-1068-3867)
Institutions
- Yonsei University (KR)
- Amorepacific (South Korea) (KR)
Publication Details
- Journal
- Annals of Dermatology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5021/ad.25.003
- Primary Topic
- Air Quality and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Health and Welfare
- Korea Health Industry Development Institute