Onset of tics in an elderly patient undergoing androgen deprivation therapy for prostate cancer: a case report

Motor and vocal tics typically manifest during childhood. Less often, tics can occur due to the use of substances or medications which raise dopamine levels. This case report describes an unusual occurrence of tics in an elderly man undergoing androgen deprivation with Goserelin for prostate cancer. Comprehensive assessments ruled out infectious, metabolic, psychiatric, and neurological conditions. The tics resolved with low-dose Risperidone, without adverse effects. This case underscores the potential for medication-induced tics in older adults, highlighting the need for increased awareness among healthcare providers regarding the neuropsychiatric effects of cancer therapies. Future research should further investigate these phenomena and their implications for treatment strategies.

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Publication Details

Journal
Oxford Medical Case Reports
Published
2025-03-01
DOI
https://doi.org/10.1093/omcr/omae206
Primary Topic
Obsessive-Compulsive Spectrum Disorders
Type
article
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0.00
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article

Onset of tics in an elderly patient undergoing androgen deprivation therapy for prostate cancer: a case report

Furaha Serventi, Leila Mwakipunda, Kim Madundo, Godwin Nnko et al.
1 links
Oxford Medical Case Reports
Obsessive-Compulsive Spectrum Disorders
article

Onset of tics in an elderly patient undergoing androgen deprivation therapy for prostate cancer: a case report

Furaha Serventi, Leila Mwakipunda, Kim Madundo, Godwin Nnko, Glory Makupa
article en

Abstract

Motor and vocal tics typically manifest during childhood. Less often, tics can occur due to the use of substances or medications which raise dopamine levels. This case report describes an unusual occurrence of tics in an elderly man undergoing androgen deprivation with Goserelin for prostate cancer. Comprehensive assessments ruled out infectious, metabolic, psychiatric, and neurological conditions. The tics resolved with low-dose Risperidone, without adverse effects. This case underscores the potential for medication-induced tics in older adults, highlighting the need for increased awareness among healthcare providers regarding the neuropsychiatric effects of cancer therapies. Future research should further investigate these phenomena and their implications for treatment strategies.

Oxford Medical Case ReportsVol. 2025(3)
Kilimanjaro Christian Medical Centre (TZ)
Openalex Percentile: Top 93%
Obsessive-Compulsive Spectrum Disorders
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Onset of tics in an elderly patient undergoing androgen deprivation therapy for prostate cancer: a case report — Furaha Serventi, Leila Mwakipunda, et al. · Oxford Medical Case Reports (2025) | TGRS Research Map | TGRS