Molecular and Genetic Insights Into Human Ovarian Aging From Single-Nuclei Multi-omics Analyses
(Abstracted from Nat Aging 2024. doi: 10.1038/s43587-024-00762-5) Ovaries are the crux of the female reproductive system and are the first organs to show signs of aging and thus the slowing of reproductive processes, characterized by a reduced number and quality of oocytes. The more a woman ages, the higher the risk of infertility or aneuploidy and congenital disabilities in their children.
Authors
- Michael G. Rosenfeld (ORCID: https://orcid.org/0000-0002-1572-156X)
- Judith Campisi (ORCID: https://orcid.org/0000-0001-6858-9462)
- Rogerio A. Løbo (ORCID: https://orcid.org/0000-0002-1472-8313)
- Jan Vijg (ORCID: https://orcid.org/0000-0002-8457-9595)
- Adam D. Hudgins (ORCID: https://orcid.org/0000-0002-2737-6839)
- Chen Jin (ORCID: https://orcid.org/0000-0003-4075-4723)
- Jan H.J. Hoeijmakers (ORCID: https://orcid.org/0000-0003-3526-7795)
- Xizhe Wang
- Zev Williams (ORCID: https://orcid.org/0000-0001-8563-3250)
- Mingzhuo Pei
- Melody Devos (ORCID: https://orcid.org/0000-0002-5601-9769)
- Daniela Contreras (ORCID: https://orcid.org/0000-0001-7907-5870)
- Yousin Suh (ORCID: https://orcid.org/0000-0002-6014-3084)
- Jiping Yang (ORCID: https://orcid.org/0000-0001-6332-8693)
- Seung-Soo Kim
- Qinghua Guo (ORCID: https://orcid.org/0000-0002-4469-5997)
- Marco Conti (ORCID: https://orcid.org/0000-0003-4755-9146)
- Amir Gamliel
Publication Details
- Journal
- Obstetrical & Gynecological Survey
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1097/ogx.0000000000001382
- Citations
- 1
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 1.88