Deep learning analysis of MRI accurately detects early-stage perihilar cholangiocarcinoma in patients with primary sclerosing cholangitis
The 3D DenseNet-121 MRI model effectively detects early-stage pCCA in PSC patients. Compared to expert radiologists, the model missed fewer cases of cancer.
Authors
- Julie K. Heimbach (ORCID: https://orcid.org/0000-0002-3567-1328)
- Shahriar Faghani (ORCID: https://orcid.org/0000-0003-3275-2971)
- Gregory James Gores (ORCID: https://orcid.org/0000-0003-3151-009X)
- Sumera I. Ilyas (ORCID: https://orcid.org/0000-0002-2709-3003)
- Bradley J. Erickson (ORCID: https://orcid.org/0000-0001-7926-6095)
- Nicholas F. LaRusso (ORCID: https://orcid.org/0000-0003-3266-0831)
- Kristin Kaasen Jørgensen (ORCID: https://orcid.org/0000-0002-3693-7706)
- John E. Eaton (ORCID: https://orcid.org/0000-0002-8029-4947)
- Konstantinos N. Lazaridis (ORCID: https://orcid.org/0000-0002-0437-681X)
- Aliya Gulamhusein (ORCID: https://orcid.org/0000-0003-4648-4736)
- Tayyab S. Diwan (ORCID: https://orcid.org/0000-0002-4153-4469)
- Anne Negård (ORCID: https://orcid.org/0000-0002-7624-5595)
- Byron H. Smith (ORCID: https://orcid.org/0000-0001-9318-2437)
- Trine Folseraas (ORCID: https://orcid.org/0000-0003-2011-1923)
- Mette Vesterhus (ORCID: https://orcid.org/0000-0003-1493-2303)
- Timuçin Taner (ORCID: https://orcid.org/0000-0003-0641-2930)
- Kartik Jhaveri
- Sudhakar K. Venkatesh (ORCID: https://orcid.org/0000-0002-7514-1030)
- Ida Bjoerk
- Andreas Abildgaard (ORCID: https://orcid.org/0000-0002-5501-259X)
- Kosta Petrovic
- Christopher L. Welle (ORCID: https://orcid.org/0000-0001-7864-9190)
- Yashbir Singh (ORCID: https://orcid.org/0000-0002-5848-7072)
- Tom H. Karlsen
Institutions
- Oslo University Hospital (NO)
- University Health Network (CA)
- Mayo Clinic (US)
- Eaton (Taiwan) (TW)
- University of Oslo (NO)
- University of Toronto (CA)
- Akershus University Hospital (NO)
- Haukeland University Hospital (NO)
- WinnMed (US)
- Mayo Clinic in Arizona (US)
- Toronto Liver Centre (CA)
- University of Bergen (NO)
Publication Details
- Journal
- Hepatology
- Published
- 2025-03-20
- DOI
- https://doi.org/10.1097/hep.0000000000001314
- Citations
- 8
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 10.58