In Reply:

In Reply: We appreciate the thoughtful comments regarding our study in the February 2025 issue.1 After thoroughly reviewing these comments and discussing them within the investigating team, we would like to address the points raised. Regarding the follow-up duration, our current protocol dictates a follow-up of patients until their first menstrual period after treatment, with outcome measures assessed during this timeframe; an additional transvaginal ultrasonogram is recommended at this timepoint. Although this approach may differ from fixed timepoint follow-up, we believe it better reflects the physiologic recovery process after early pregnancy loss and does better ensure that no negative outcomes are overlooked. Concerning the selection of variables for our multivariable analysis, we included factors that were either previously established as significant predictors of treatment success or showed statistical significance in our univariate analysis. Prior vaginal deliveries were included based on existing evidence demonstrating their association with improved treatment outcomes.2–4 Although we acknowledge the potential importance of body mass index (BMI) and recent vaginal bleeding as predictors, unfortunately, we were unable to extract these data from our medical records because they were not consistently noted, thereby preventing their inclusion in the analysis. Regarding the article title, it was modified during the peer-review process to align with current terminology in the field. However, we agree that greater specificity would be beneficial, and we appreciate this suggestion for future work in this area.

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Publication Details

Journal
Obstetrics and Gynecology
Published
2025-03-20
DOI
https://doi.org/10.1097/aog.0000000000005863
Primary Topic
Reproductive Health and Contraception
Type
article
Field-Weighted Citation Impact
0.00
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In Reply:

Ram Kerner, Liat Mor, Ohad Gluck, Matan Friedman et al.
Obstetrics and Gynecology
Reproductive Health and Contraception
article

In Reply:

Ram Kerner, Liat Mor, Ohad Gluck, Matan Friedman, Ron Sagiv, N. L. M. Paul, Ran Keidar, Rotem Shazar
article en

Abstract

In Reply: We appreciate the thoughtful comments regarding our study in the February 2025 issue.1 After thoroughly reviewing these comments and discussing them within the investigating team, we would like to address the points raised. Regarding the follow-up duration, our current protocol dictates a follow-up of patients until their first menstrual period after treatment, with outcome measures assessed during this timeframe; an additional transvaginal ultrasonogram is recommended at this timepoint. Although this approach may differ from fixed timepoint follow-up, we believe it better reflects the physiologic recovery process after early pregnancy loss and does better ensure that no negative outcomes are overlooked. Concerning the selection of variables for our multivariable analysis, we included factors that were either previously established as significant predictors of treatment success or showed statistical significance in our univariate analysis. Prior vaginal deliveries were included based on existing evidence demonstrating their association with improved treatment outcomes.2–4 Although we acknowledge the potential importance of body mass index (BMI) and recent vaginal bleeding as predictors, unfortunately, we were unable to extract these data from our medical records because they were not consistently noted, thereby preventing their inclusion in the analysis. Regarding the article title, it was modified during the peer-review process to align with current terminology in the field. However, we agree that greater specificity would be beneficial, and we appreciate this suggestion for future work in this area.

Obstetrics and GynecologyVol. 145(4)
Wolfson Medical Center (IL)
Openalex Percentile: Top 92%
Reproductive Health and Contraception
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In Reply: — Ram Kerner, Liat Mor, et al. · Obstetrics and Gynecology (2025) | TGRS Research Map | TGRS