CTCF-anchored chromatin loop dynamics during human meiosis

Overall, we find that chromatin loops do not orchestrate the gene expression dynamics seen during spermatogenesis, but loops do play important roles in recombination, influencing the positions of DNA breakage and cross over events.

Authors

Colin A. Semple (ORCID: https://orcid.org/0000-0003-1765-4118)
Vera B. Kaiser (ORCID: https://orcid.org/0000-0003-0619-6297)

Institutions

Western General Hospital (GB)
University of Edinburgh (GB)

Publication Details

Journal: BMC Biology
Published: 2025-03-20
DOI: https://doi.org/10.1186/s12915-025-02181-3
Primary Topic: Genomics and Chromatin Dynamics
Type: article
Field-Weighted Citation Impact: 0.00

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article

CTCF-anchored chromatin loop dynamics during human meiosis

Colin A. Semple, Vera B. Kaiser

Mar 20, 2025

BMC Biology

Genomics and Chromatin Dynamics

article

CTCF-anchored chromatin loop dynamics during human meiosis

Colin A. Semple, Vera B. Kaiser

March 20, 2025article en

Abstract

BMC BiologyVol. 23(1)

Western General Hospital (GB), University of Edinburgh (GB)

Openalex Percentile: Top 95%

Genomics and Chromatin Dynamics

DOI Open Access PDF OpenAlex

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CTCF-anchored chromatin loop dynamics during human meiosis — Colin A. Semple, Vera B. Kaiser · BMC Biology (2025) | TGRS Research Map | TGRS