Evodiamine Promotes Autophagy and Alleviates Oxidative Stress in Dry Eye Disease Through the p53/mTOR Pathway
These findings suggest that EVO is a potential therapeutic agent for the treatment of DED, with its beneficial effects attributed to the activation of autophagy through the p53/mammalian target of rapamycin pathway.
Authors
- Kai Hu (ORCID: https://orcid.org/0009-0001-6910-9413)
- Jiaxuan Jiang (ORCID: https://orcid.org/0000-0002-7889-5209)
- Taige Chen (ORCID: https://orcid.org/0000-0003-1660-1348)
- Di Zhang (ORCID: https://orcid.org/0000-0002-0228-5244)
- Junpeng Liu (ORCID: https://orcid.org/0000-0001-9222-3663)
- Yiran Chu
- Boda Li (ORCID: https://orcid.org/0000-0002-6698-8635)
- Jia-Ruei Tsao
- Zeying Chen
Institutions
- Nanjing University of Chinese Medicine (CN)
- Nanjing Drum Tower Hospital (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-03-20
- DOI
- https://doi.org/10.1167/iovs.66.3.44
- Citations
- 7
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 13.15