Evaluation of [125I]α-Bungarotoxin Binding to α7 Nicotinic Acetylcholinergic Receptors in Hippocampus–Subiculum of Postmortem Human Alzheimer’s Disease Brain
[<sup>125</sup>I]α-Bgtx shows complimentary potential as a α7 nAChR imaging agent but needs more preclinical assessments to confirm effectiveness for translational PET studies using α7 nAChR radioligands.
Authors
- Christopher Liang (ORCID: https://orcid.org/0000-0001-9081-294X)
- Tram B. Danh
- Oshini V. Keerthisinghe
- Fariha Karim (ORCID: https://orcid.org/0009-0001-3104-9523)
- Jogeshwar Mukherjee (ORCID: https://orcid.org/0000-0003-1009-877X)
- Ambrose Loc T Ngo (ORCID: https://orcid.org/0009-0002-6993-9131)
Institutions
- University of California, Irvine (US)
Publication Details
- Journal
- Receptors
- Published
- 2025-03-20
- DOI
- https://doi.org/10.3390/receptors4010007
- Citations
- 3
- Primary Topic
- Nicotinic Acetylcholine Receptors Study
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- National Institutes of Health