Seasonal variations in circulating endocannabinoidome mediators and gut microbiota composition in humans
This study identified specific seasonal changes in gut microbiota composition and circulating levels of several NAEs, which were not associated with vitamin D status and lifestyle habits. It underscores the importance of the gut microbiota-endocannabinoidome axis in the pathophysiology of seasonal changes, and of considering seasons in clinical trials on these systems.
Authors
- Sophie Castonguay-Paradis
- Sébastien Lacroix (ORCID: https://orcid.org/0000-0001-8057-8774)
- Julie Perron (ORCID: https://orcid.org/0000-0001-7454-7840)
- Frédéric Raymond (ORCID: https://orcid.org/0000-0002-3606-4060)
- Élisabeth Demers‐Potvin (ORCID: https://orcid.org/0000-0001-8315-0132)
- Nicolas Flamand (ORCID: https://orcid.org/0000-0001-5944-7200)
- Cyril Martin (ORCID: https://orcid.org/0000-0002-7371-1888)
- Gabrielle Rochefort
- Alain Veilleux (ORCID: https://orcid.org/0000-0003-4078-1908)
- Vincenzo Di Marzo
Institutions
- Institut universitaire de cardiologie et de pneumologie de Québec (CA)
- Université Laval (CA)
Publication Details
- Journal
- Gut Microbes
- Published
- 2025-03-20
- DOI
- https://doi.org/10.1080/19490976.2025.2476563
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00